Anti- N-methyl-d-aspartate receptor encephalitis in an older patient presenting with a rapid onset of delusions and amnesia

Zoya Marinova; Nikolaus Bausch-Becker; Egemen Savaskan

doi:10.1136/bcr-2018-228512

Anti- N-methyl-d-aspartate receptor encephalitis in an older patient presenting with a rapid onset of delusions and amnesia

BMJ Case Rep. 2019 Apr 15;12(4):e228512. doi: 10.1136/bcr-2018-228512.

Authors

Zoya Marinova¹, Nikolaus Bausch-Becker¹, Egemen Savaskan¹

Affiliation

¹ Clinic for Geriatric Psychiatry, Psychiatric University Clinic, Zurich, Switzerland.

Abstract

We present the case of a 77-year-old patient with a rapid onset of delusions, amnesia, agitation, insomnia and no previous psychiatric history, who was diagnosed with anti-N-methyl-d-aspartate receptor encephalitis. This case report highlights the importance of including autoimmune encephalitis in the differential diagnosis of older patients presenting with rapid onset psychiatric episodes.

Keywords: neurology (drugs and medicines); psychiatry (drugs and medicines).

Publication types

Case Reports

MeSH terms

Acute Disease
Aged
Amnesia / etiology
Anti-N-Methyl-D-Aspartate Receptor Encephalitis / cerebrospinal fluid
Anti-N-Methyl-D-Aspartate Receptor Encephalitis / diagnosis*
Anti-N-Methyl-D-Aspartate Receptor Encephalitis / drug therapy
Delusions / etiology
Diagnosis, Differential
Humans
Immunoglobulin A / administration & dosage
Male
Psychomotor Agitation / etiology
Receptors, N-Methyl-D-Aspartate / immunology*

Substances

Immunoglobulin A
Receptors, N-Methyl-D-Aspartate